1. A type of gene therapy called RNA interference (RNAi) is being investigated t

1. A type of gene therapy called RNA interference (RNAi) is being investigated to treat Huntingtons Disease a disease where a misfolded protein forms clump in neural tissue. The techniques involve synthesizing short sequences of RNA (siRNA or small interfering RNA) that forms base pairs with the mRNA that codes for this protein. Why in theory would this strategy work to combat this disease and what is the largest obstacle that scientists have to overcome to make this strategy more successful.2. In humans the urge to breathe results from high concentration of CO2 in the blood there are no direct physiological sensors of pO2. Explain why this observation makes sense.3. Does a strong acid have a greater or lesser tendency to lose a proton than a weak acid? Which one has a higher value for Ka? Explain.