Define and give the formula for an odds ratio:Complete the 2 x 2 table below and

Define and give the formula for an odds ratio:Complete the 2 x 2 table below and calculate the Odds Ratio: There were 91 total with lung cancer of which 27 were not exposed to tobacco smoke; 173 total without lung cancer of which 56 were exposed to tobacco smoke. Show your work.Disease StatusYesNoExposure StatusYes6456No271173) Interpret the odds ratio / what does this finding mean?4) You are reviewing the results of a case-control study of vitamin D supplements and prostate cancer. The study had an alpha level of .05 and 95% CI. The study findings report an Odds Ratio of .49 p value = .001 95% CI (.45 .60). Interpret these results: comment on the OR p value and CI.5) Discuss some of the methodological limitations of the case-control study design.